Sermorelin half-life & how long it lasts
Sermorelin has a half-life of about 12 minutes, reaches peak concentration around 12 minutes after a dose, and is practically cleared from the body about 1 hours after the last dose. Cleared in minutes rather than hours — roughly an 11 to 12 minute half-life in the published work.
The numbers
| Half-life | 12 minutes |
|---|---|
| Time to peak | 12 minutes |
| Route | injection |
| Typical cadence | daily protocols vary |
| Practically cleared | 1 hours after the last dose (five half-lives, ~97% eliminated) |
| Steady state | after roughly 1 hours of continuous daily protocols vary dosing |
| Evidence | FDA label or published human PK |
What that means day to day
- Levels are never zero between doses. On a daily protocols vary schedule with a 12 minutes half-life, each dose stacks on what is left of the last one until steady state.
- Peak is not injection day. Concentration keeps climbing for about 12 minutes after the shot, so effects and side effects lag the dose.
- Stopping is gradual. After the last dose it takes about 1 hours for the compound to be practically gone.
Sources
Track it instead of estimating it
Bo models this curve from your own logged doses, so you can see what is still in your system right now instead of doing the arithmetic. It also handles reconstitution math, dose reminders and injection-site rotation.
Compare every compound in one table →
Educational information only. Bo is a tracking app, not a medical device, and nothing here is medical advice, a dosing recommendation, or a substitute for your prescriber. Half-lives are population averages from the sources cited on each row; individual clearance varies with body weight, kidney and liver function, and other medication.